David Byrne is a Quaker

mental_floss Blog: Richard Nixon and 12 Other Quakers You Didn't Know:

"According to TalkingHeads.net, the musician to-be was regularly encouraged by his mother's 'tolerant Quaker philosophies.' That, along with the constant drone of Scottish and American folk music in the house, supposedly played a large role in his eventual career choice."

Also, it probably had something to do with, by his own account, that song his mother used to sing to him when he was little.